Technical Information

Papers appearing here deal with more technical matters, along with a few reviews. Depending on your background, some of this material may seem pretty intense. When in doubt, my suggestion is to give it a try - even with highly complex topics, most scientists are very good at communicating to a lay audience. Some, of course, are terrible. Give it a shot!


(From) Basic Science to Blockbuster Drug: the Discovery of Lyrica a fascinating account of the development of pregabalin (Lyrica®), the incredibly successful followup to Neurontin. An amazing story!.

Cardiovascular Disease
"As a recognized worldwide leader in CVD testing, Siemens Healthcare Diagnostics provides a comprehensive and expanding menu of cardiac biomarkers across a broad spectrum of instrument solutions that help manage patients throughout the continuum of cardiovascular disease."

Chronic Pain MedicineNet's great chronic pain article

Innovations in Drug Treatment for Pain  U. TX Cancer Center

Neuropathic Pain
107-slide presentation (HTML) by Dr. Kim Burchiel of OR Health Sci. Univ. A superlative learning device!

OHSU newsletter focusing on RSD

Outline Curriculum on Pain (Overview)

Pain and Its Control (Oxford) a very nice, outline-style article with excellent indexing

Pain Research at Oxford short description of research into pain at Oxford Univ.

Randomized controlled trial of gabapentin in CRPS I excellent article on gabapentin (Neurotin®) in CRPS/RSD

Relief of Chronic NonMalignant Pain (Oxford Univ.) a long, scholarly treatise on treating chronic pain

Spinal Cord Stimulators short review from OHSU

Suicide Information and Education Center Suicide Prevention, Research, Training, Scientific Articles, Newsletters, etc.

Systematic review of intravenous regional sympathectomy for RSD
"Chronic non-malignant pain is often difficult to treat, and performing randomised controlled trials (RCTs) in persons with these pains raises many practical and ethical problems. "

Systematic Reviews on Pain Topics somewhat dated (2004) but very complete (nearly 700 references) listing of published reviews on the multitude of topics of interest to anyone whose life is involved with pain of some kind.

Univ. of Mich. Anesthesiology Home Page "The Department's mission is to provide excellent patient care, educate future anesthesiologists and conduct laboratory and clinical research in the field."

Univ. of Utah's "Neurological Processes of Pain"  a great four-part series of animations (you need the shockwave plugin for several) on the neurology of pain signal transmission - kind of deep, but can be followed if you pay attention

Wheeless' Textbook of Orthopædics "This is the most comprehensive, unparalleled, dynamic online medical textbook in existence. Looking through our 11,000 pages with more than 5,000 images, you'll find this key reference in an easy to read outline format. Each topic is fully searchable by alphabetical, anatomical and keyword searches, or just click on a particular part of the Skeleton for easy access. Wheeless' Textbook of Orthopaedics is updated daily."